Psychedelics & medical cannabis

A good trip for investors?

Last updated: 28 Jul 2022

Market 101

Forget popping pills at a rave or escaping to a hippie commune: if a new wave of startups have it their way, the future of psychedelics and cannabis will lie in controlled clinical settings complete with prescriptions and therapists. They’re pushing for a renaissance and a rebrand of drugs that’s all about science, not excess, and healing, not getting high.

With their products already in use in an increasing number of European countries, medical cannabis startups are further along this path than psychedelics startups, which are seeking to create a market from scratch — that is, once they’ve identified the best compounds for treatment and received regulatory approval. What ties the two together is the need for a methodical process to build trust in this new age of recreational drug turned therapeutic.

Early stage market map

Early stage market map

Key stats

€13.8tn

projected costs of mental disorders by 2030 (including lost productivity)1

400m

number of Europeans who have legal access to medical cannabis2

€357m

projected sales of medical cannabis in Europe in 20223

Startups tracked by Sifted

Investors by type

Sifted take

With laws becoming more lenient across Europe, the biggest barrier that medical cannabis startups still need to cross is the buy-in of doctors and physicians. In preparing for after their drug discovery efforts bear fruition, psychedelics startups would also do well to outline strategies to win over these key partners.

Rising stars

We identify companies as ‘rising stars’ using a number of criteria including founder backgrounds, investor track record, funding and valuation, and growth signals.

Clerkenwell Health

Psychedelics

Total funding

€2.2m

London, United Kingdom
2020

Has opened Europe's first commercial psychedelic research facility in London which provides the infrastructure drug development companies need to run clinical trials - for now focusing on psilocybin

Round

Seed


Date

2021

Size

€1.8m

Octarine Bio

Psychedelics

Total funding

€2.7m

Copenhagen, Denmark
2018

Drug development company that uses yeast fermentation to produce psychedelics compounds which can otherwise be difficult to make in the quality required for clinical development.

Round

Seed

Valuation

Undisclosed


Date

2021

Size

€1.1m

Piauhy

Cannabis

Therapeutics

Total funding

€4m

Lisbon, Portugal
2019

Developing cannabinoid therapeutics for conditions that include autism, epilepsy and Alzheimer's. Founder Eduardo Sampaio previously cofounded Australia's fisrt marketplace fo hemp food products.

Round

Seed

Valuation

€40m


Date

2021

Size

€3m

Early stage startups to watch

Alphagreen Group

London, United Kingdom
2019
Pre-seed

4.1m

2.8m

14.6m

AVIDA Global

London, United Kingdom
2018
Seed

3.2m

1.3m

-

Becanex

Berlin, Germany
2019
Seed

770k

770k

-

Canax

Milan, Italy
2019
Seed

1.3m

1.3m

-

Cannaable

Landau in der Pfalz, Germany
2019
Seed

500k

500k

-

Clerkenwell Health

London, United Kingdom
2020
Seed

2.2m

1.8m

11.2m

Daye

London, United Kingdom
2018
Seed

5m

5m

-

Grass & Co.

London, United Kingdom
2018
Seed

2.5m

1.2m

7.5m

GreenLight Medicines Ltd

Dublin, Ireland
2014
Seed

2.4m

600k

9.4m

Grow

London, United Kingdom
2017
Seed

-

4.2m

-

Highline Wellness

Blackpool, United Kingdom
2019
Seed

-

3.6m

-

Neurocentrx

Edinburgh, United Kingdom
2013
Seed

-

-

-

Octarine Bio

Copenhagen, Denmark
2018
Seed

2.7m

1.1m

-

ohne

London, United Kingdom
2019
Seed

750k

910k

-

Piauhy

Lisbon, Portugal
2019
Seed

4m

3m

40m

ProfesorCBD

Madrid, España
2018
Series B

1.3m

1m

6.6m

Puresport

London, United Kingdom
2018
Angel

250k

250k

320k

Rainbow

Paris, France
2019
Seed

3m

2m

12m

Signature Products GmbH

Pforzheim, Germany
2019
Grant

1.3m

800k

5m

Tetra Pharm Technologiesc

Hillerød, Denmark
2020
Seed

2m

2m

-

Thankyoujane / Cantura

Germany
2017
Seed

-

300k

-

The Beemine Lab

Madrid, Spain
2018
Seed

1.2m

900k

-

Voyager CBD

Perth, United Kingdom
2020
Seed

1.2m

1.2m

-

Wavepaths

London, United Kingdom
2018
Seed

4.1m

4.1m

-

Yamnaya

Madrid, Spain
2020
Seed

350k

350k

-

Europe’s success stories

Who early stage startups are up against

(Pre-)Seed

SeriesA

SeriesB

SeriesC

SeriesD+

IPO/Exit

→ €1.9bn market cap

→ Has patented a synthetic version of psilocybin to treat depression

(Pre-)Seed

SeriesA

SeriesB

SeriesC

SeriesD+

IPO/Exit

→ €1.3bn market cap

→ Owns 10 companies each working on a different compound to treat mental health issues

(Pre-)Seed

SeriesA

SeriesB

SeriesC

SeriesD+

IPO/Exit

→ Vertically integrated cannabis company acquired for over €300m by Curaleaf

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