Nanotech
Can the very, very small go big?
Last updated: 21 Jul 2022
Market 101
What if we could manipulate something that’s 100k times thinner than the width of paper to create new, powerful tech? What sounds like fantasy is in fact the domain of nanotechnology, where absolutely tiny materials are reshaped to create cutting edge products, like batteries that last longer, anti- cancer drugs, or filters that make polluted water drinkable.
Alongside excitement in the field, though, there are questions about just how widely and profitably this tech will be used. For now commercial nanotech is mostly limited to products that have been incrementally enhanced through the selective use of nano-enabled materials or processes. Their more revolutionary counterparts remain stuck in the lab. It will take a combo of fundamental research around matter dynamics at the nanoscale; the ability to mass-manufacture nanoparticles; and more stringent standards around testing and usage to see truly revolutionary nanotech take its long-promised leap out of the lab and into the everyday.
Early stage market map
Key facts
1nm (nanometre)
one billionth of a metre — or how long our fingernails grow per second1
$8bn
global nanomaterials market in 20202
14
% projected CAGR of the global nanomaterials market from 2021-20283
Trends to watch
1. Micro machines
→ Electronics is one of the subsectors where the application of nanotech is at its most advanced, with semiconductors relying on ever smaller and more powerful transistors.
→ The challenge is to develop manufacturing processes that can keep up with the increasing sophistication of components while limiting skyrocketing costs.
2. Targeted medicine
→ Nanomedicine — attaching microparticles to drugs — holds the promise of targeting only diseased cells and avoiding healthy ones, as well as releasing drugs in a more controlled way.
→ Holding back these applications is a broader lack of understanding around the efficacy of drugs across a large patient population.
A new era for electric cars?
→ Incorporating nanomaterials like graphene — a “wonder material” made of a single layer of carbon atoms — into lithium-ion batteries expands their energy-generating surface area and thus improves energy density.
→ The biggest challenge for startups developing these components remains cost, forcing them to demonstrate capabilities that are advanced enough to justify the price of their batteries.
4. Reap what you nano-sow
→ Similar to drug delivery, nanotechnology could be used in agriculture to improve the efficiency of fertilisers and pesticides by letting them be absorbed precisely where in the plant they’re needed and in the correct quantities.
→ Nanobiosensors are another application, opening up the possibility of monitoring crop stress and soil health in real time and at much higher sensitivity and specificity than conventional biosensors.
Startups tracked by Sifted
Sifted take
For all the promise that nanotech holds, there are still many uncertainties when it comes to application. Cost and safety remain key concerns, both with regards to access to nanotech-based products and the risk of nanoparticles released into the environment more broadly. Rigorous testing will be central to build trust and encourage adoption.
Rising stars
Europe's leading pre-Series A startups (all published data verified) We identify companies as ‘rising stars’ using a number of criteria including founder backgrounds, investor track record, funding and valuation, and growth signals
Total funding
€7m
Based just outside of Amsterdam, E-magy uses “environmentally benign” silicon anode material to boost the performance of lithium-ion batteries. Company is backed by SHIFT Invest and PDENH.
Round
Seed
Date
2021
Size
€5m
Backed by the likes of Bpifrance, 360 Capital Partners and Agoranov, C12 QE uses pure carbon nanotubes to produce quantum processors and hybrid circuits. Cofounders and twin brothers Pierre and Matthieu Desjardins have notable academic track records in the field.
Round
Seed
Valuation
€45m
Date
2021
Size
€9.1m
A European Innovation Council grant winner among 4,000 companies, Dublin-based RemedyBio develops nanoscale biotechnology for therapeutic and diagnostic discovery for different applications, including immuno-oncology and infectious diseases.
Round
Seed
Date
2021
Size
€8m
Early stage startups to watch
AlixLabs
Manufacturing
Semiconductors
€910k
€910k
€2.9m
ATLANT 3D Nanosystems
Manufacturing
€870k
€750k
€6.5m
BIOND Solutions (BI/OND)
Drug diagnostics & therapeutics
€3.9m
€2.5m
-
C12 Quantum Electronics
Quantum applications
€9.1m
€9.1m
€45m
Carbon Waters
Graphene-based solutions
€2.3m
€770k
€5.3m
E-magy
Energy,Transportation
Advanced battery materials
€7m
€5m
-
ELDICO SCIENTIFIC
Manufacturing
Nano-cristallography
€4m
€2.5m
-
Gelatex Technologies
Alternative materials
Nanofibers
€1.6m
€1.2m
-
Infrascreen
Alternative materials
€1.5m
€1.5m
-
Innatera Nanosystems
Chips & processors
€5m
€5m
-
Kimialys
Drug diagnostics & therapeutics
€100k
€100k
-
NUCAPS Nanotechnology
Nanocapsules
€2.5m
€5m
-
QDI Systems
Drug diagnostics & therapeutics
Imaging
€1.6m
€1.3m
-
Remedy Biologics
Drug diagnostics & therapeutics
€18.5m
€8m
-
Sources
Research reports
2, 3 Nanomaterials Market Size & Share Report, 2021-2028 | Grandview Research
News articles
Nanotechnology in Medicine: Technology trends | June 2022 | Medical Device Network
How nanotechnology can benefit smart cities | November 2021 | Nanowerk
The latest nanotechnology advances for agriculture | April 2021 | Nanowerk
Nanom's nanotech makes more efficient batteries that last at least 9 times longer | April 2021 | VentureBeat
Looking to Nature for the Next Industrial Revolution | March 2021 | BCG
How Agricultural Nanotechnology Will Influence the Future of Farming Sustainability | February 2021 | Azonano
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