Longevity (2024)
These startups will add years to your life
Last updated: 15 Feb 2024
Market 101
Miracle gene-altering drugs, cell-reprogramming and cryogenic chambers: we don’t always associate longevity with serious scientific undertakings so much as wacky activities that the super rich do to cheat death.
Truthfully, there’s a lot of crazy attempts to reverse ageing or to find an actual “cure” for dying. But most people in the field want to improve quality of life, or the end of life, when traditional medicine hasn’t helped enough. Longevity is about understanding how our cells wear out over time and trying to reverse this and keep age-related diseases at bay. It's also about preventive care — spotting and tackling problems before they occur.
In 2023, longevity-specific startups raised $126m in Europe, a drop from the $366m the sector saw in 2022. The field includes a raft of companies promising to deliver a better gauge of health, with detailed insights into the microbiome and the immune system, among other things. Some are selling at-home test kits for a few hundred euros apiece; others are developing sophisticated treatments running into the thousands of euros.
No one has embraced longevity quite like the Silicon Valley heavyweights — techies including Sam Altman, Larry Ellison, Jeff Bezos, Yuri Milner and Peter Thiel have collectively spent billions on the business of living longer. If longevity sometimes feels like a luxury for the very wealthy, that’s because it often is: visiting a “cheap” longevity clinic can set you back €460 a month, while stem cell treatments can hit you for €20k.
Europe hasn’t seen massive investor splurges, though it has its longevity proponents too: German billionaire Christian Angermayer is probably the most prolific longevity backer in the region. European family offices are particularly interested in the sector too, says Phil Newman, founder of longevity investment brokerage First Longevity.
Other interested investors in Europe include Atomico and General Catalyst, which both backed Spotify billionaire Daniel Ek's latest venture, diagnostics company Neko Health, which collects patient data on the skin, the heart, vessels, respiration, inflammations and more. Pharma companies are also pushing longevity boundaries. Novo Nordisk’s diabetes treatment Ozempic — arguably the world’s most famous drug — has shown promising results for repairing DNA damage in mice, so there’s hope that it can eventually reduce the risk of many ailments.
Founders tell us death is just another problem to solve. But even as tech progresses and wallets open, there’s a lot we don’t know about ageing or how to slow it. Research still has a long way to go before it can show us that what works on mice will also work on humans.
Early stage market map
Key facts
81
years is the average life expectancy for European women1
75
years is the average life expectancy for European men2
30%
of the EU's population will be aged 65 and over by 21003
Trends to watch
Is the field too exclusive?
- Why do we only hear about billionaires trying out longevity treatments? Because most of the existing longevity clinics and stem cell treatments are not pocket-friendly.
- Still, there are some affordable options for tracking how well we’re ageing that go beyond conventional measures like blood pressure and body mass index.
- For example, UK startup GlycanAge offers at-home test kits that help determine your biological age for £289 a pop. Another UK-based startup, Muhdo, sells “spit-and-send” tests which the company says are able to monitor and track changes to your genes.
- It's a growing market for DIY kits: there's also a gut health test from UK healthtech Zoe for €300 and a blood sugar level gauge from Finnish startup Veri for €139 a month.
Will longevity clinics become the new spa retreats?
- European anti-ageing spa retreats will soon encounter competition from clinics offering not only skin rejuvenation, but also longevity enhancement through biohacking and anti-ageing therapies.
- Watch out for three longevity clinics opening in Europe this year: Maximon’s Ayun in Zurich, Apollo Health's longevity clinic in Germany and a similar establishment in Stockholm.
- Although membership will probably hover around €500 per month initially, as the market grows, we could see prices fall.
Man and machine will merge
- The day is coming when people and computers will combine through brain-computer interfaces, according to longevity investor Christian Angermayer.
- “We’re merging with it [AI]," he said at Sifted Summit. “But it frightens people because suddenly, it changes a bit what it means to be human… I can totally see that in 50 years, we [will] have evolved to another species.”
Startups tracked by Sifted
Sifted take
The centenarians are coming. Life expectancy will approach triple digits this century — and startups think they can go several years beyond this. While we don't know if anyone can truly breach the upper limits of life — don't expect to see the 150 year old human any day soon — interest in anti-ageing startups will remain strong. Tech leaders will continue to amass astonishing wealth — and a good chunk of this will be invested in prolonging a meeting with the Grim Reaper.
Rising stars
Aware is a mobile app that gives users tips to improve their health. How it works in more detail: users are pointed to a nearby clinic and afterwards get tailored recommendations. Cofounded by Florian Meissner and Ferdinand Schmidt-Thomé, the seed round was led by VC firm Lakestar, along with Berlin-based investors Cherry Ventures and June Fund.
Round
Seed
Valuation
Undisclosed
Date
2022
Size
€10m
Zoī combines routine medical checkups with preventive care through an app. Cofounders Ismaël Emélien — former special advisor to Emmanuel Macron — and Paul Dupuy received €20m in 2022 and launched their first medical check-up centre in 2023.
Round
Pre-seed
Valuation
Undisclosed
Date
2022
Size
€20m
This company provides biological age testing kits. Customers send four drops of blood to the lab — after the results come in, they speak to a specialist to see how their lifestyles can be optimised.
Round
Seed
Valuation
Undisclosed
Date
2023
Size
€3.8m
Neko Health, a healthtech startup focused on body scanning, co-founded by serial entrepreneur Hjalmar Nilsonne and Spotify founder Daniel Ek, completed a funding round led by Lakestar. Other notable participants included Atomico and General Catalyst.
Round
Series A
Valuation
Undisclosed
Date
2023
Size
€60m
Early stage startups to watch
Actif Age
Rejuvenation
€100k
€100k
€666k
Advosense
Diagnostics
€1.3m
€750k
-
Age Labs AS
Diagnostics
€2m
€550k
-
Aktiia
Diagnostics
€24.4m
€15.9m
-
Albert Health
Diagnostics
Rehabilitation
€910k
€910k
-
Avea Life
Preventative care
€2.4m
€2.1m
-
Aware Health GmbH
Diagnostics
€14.1m
€10m
-
Biolytica
Preventative care
€5.3m
€5.3m
-
Bioniq health-tech solutions
Preventative care
€20.7m
€13.6m
-
Care
Preventative care
€5m
-
-
Cellbricks
Cell therapeutics
€1.4m
€600k
-
Cellvie
Cell therapeutics
€9.6m
€5m
-
Cleara Biotech
Cell therapeutics
Cell therapies
€2.3m
€2.3m
-
Clock Bio
Cell therapeutics
€3.6m
€3.6m
-
Curexsys
Rejuvenation
-
-
-
-
Epiterna
Cell therapeutics
€10m
€10m
-
GlycanAge LTD
Diagnostics
€4.2m
€3.8m
€18.8m
Healthier
Preventative care
€10k
€10k
-
Lykon
Preventative care
Genetic testing
€18.9m
€2.5m
-
Muhdo
Diagnostics
-
-
-
-
Neko Health
Preventative care
€60m
€60m
-
Rosita Longevity
Preventative care
€2.4m
€2.4m
-
Samsara Therapeutics
Cell therapeutics
-
-
-
Senisca
Rejuvenation
€2.8m
€690k
-
Shift Bioscience
Rejuvenation
€6m
€5m
-
SmartQare
Diagnostics
€11.8m
€1.2m
-
Theblood
Preventative care
€1m
€1m
-
Thriva Solutions
Diagnostics
€13.7m
€4.8m
-
Una Health
Diagnostics
€2.6m
€2.3m
-
Zoī
Preventative care
€20m
€20m
€100m
Europe’s success stories
Who early stage startups are up against
(Pre-)Seed
Series A
Series B
Series C
Series D+
IPO/Exit
The UK company is working on gene therapies designed to halt or slow the ageing process. In 2022, it became the first European longevity company to go public, listing on the London Stock Exchange. Genflow was founded by Eric Leire, an expert in cell and gene therapy who has led several gene and cell therapy companies, including the Nasdaq-listed Enochian Biosciences.
(Pre-)Seed
Series A
Series B
Series C
Series D+
IPO/Exit
A company focused on developing therapies to postpone age-related diseases. In October 2023, Rejuvenate Biomed announced the completion of a six-week study for its lead drug candidate, which has shown promise in elderly male subjects with muscle atrophy.
(Pre-)Seed
Series A
Series B
Series C
Series D+
IPO/Exit
Swiss company that sells consumer health products targeting healthy ageing. Timeline raised a $66m Series D round in January 2024, which saw L’Oréal's venture arm Bold take a minority stake in the company.
Sources
Data sources
Sifted | Proprietary data
Dealroom.co | Data
1, 2 Average life expectancy in Europe for those born in 2022, by gender and region | May 2023 | Statista
News articles
13 European longevity startups hacking the ageing process | October 2023 | Sifted
New year – longer life? What longevity has to offer in 2024 | January 2024 | Sifted
5 investors explain why longevity tech is a long-term play | August 2022 | Techcrunch
How to live into your 100s — diabetes drugs, sleep and mates | October 2023 | Sifted
Venture Capital Giants In The Billion-Dollar Quest For Longevity Breakthroughs | November 2023 | Forbes
Other
3 Healthy ageing and longevity in Europe: How do we prepare for the 100-year life? | March 2024 | ilc
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