Longevity (2024)

These startups will add years to your life

Last updated: 15 Feb 2024

Market 101

Miracle gene-altering drugs, cell-reprogramming and cryogenic chambers: we don’t always associate longevity with serious scientific undertakings so much as wacky activities that the super rich do to cheat death.

Truthfully, there’s a lot of crazy attempts to reverse ageing or to find an actual “cure” for dying. But most people in the field want to improve quality of life, or the end of life, when traditional medicine hasn’t helped enough. Longevity is about understanding how our cells wear out over time and trying to reverse this and keep age-related diseases at bay. It's also about preventive care — spotting and tackling problems before they occur.

In 2023, longevity-specific startups raised $126m in Europe, a drop from the $366m the sector saw in 2022. The field includes a raft of companies promising to deliver a better gauge of health, with detailed insights into the microbiome and the immune system, among other things. Some are selling at-home test kits for a few hundred euros apiece; others are developing sophisticated treatments running into the thousands of euros.

No one has embraced longevity quite like the Silicon Valley heavyweights — techies including Sam Altman, Larry Ellison, Jeff Bezos, Yuri Milner and Peter Thiel have collectively spent billions on the business of living longer. If longevity sometimes feels like a luxury for the very wealthy, that’s because it often is: visiting a “cheap” longevity clinic can set you back €460 a month, while stem cell treatments can hit you for €20k.

Europe hasn’t seen massive investor splurges, though it has its longevity proponents too: German billionaire Christian Angermayer is probably the most prolific longevity backer in the region. European family offices are particularly interested in the sector too, says Phil Newman, founder of longevity investment brokerage First Longevity.

Other interested investors in Europe include Atomico and General Catalyst, which both backed Spotify billionaire Daniel Ek's latest venture, diagnostics company Neko Health, which collects patient data on the skin, the heart, vessels, respiration, inflammations and more. Pharma companies are also pushing longevity boundaries. Novo Nordisk’s diabetes treatment Ozempic — arguably the world’s most famous drug — has shown promising results for repairing DNA damage in mice, so there’s hope that it can eventually reduce the risk of many ailments.

Founders tell us death is just another problem to solve. But even as tech progresses and wallets open, there’s a lot we don’t know about ageing or how to slow it. Research still has a long way to go before it can show us that what works on mice will also work on humans.

Early stage market map

Key facts

81

years is the average life expectancy for European women1

75

years is the average life expectancy for European men2

30%

of the EU's population will be aged 65 and over by 21003

Startups tracked by Sifted

Sifted take

The centenarians are coming. Life expectancy will approach triple digits this century — and startups think they can go several years beyond this. While we don't know if anyone can truly breach the upper limits of life — don't expect to see the 150 year old human any day soon — interest in anti-ageing startups will remain strong. Tech leaders will continue to amass astonishing wealth — and a good chunk of this will be invested in prolonging a meeting with the Grim Reaper.

Rising stars

Aware

Health app for personalised medicine

Total funding

€14.1m

Berlin, Germany
2021

Aware is a mobile app that gives users tips to improve their health. How it works in more detail: users are pointed to a nearby clinic and afterwards get tailored recommendations. Cofounded by Florian Meissner and Ferdinand Schmidt-Thomé, the seed round was led by VC firm Lakestar, along with Berlin-based investors Cherry Ventures and June Fund.

Round

Seed

Valuation

Undisclosed


Date

2022

Size

€10m

Zoī

Healthcare tech platform

Total funding

€20m

Paris, France
2021

Zoī combines routine medical checkups with preventive care through an app. Cofounders Ismaël Emélien — former special advisor to Emmanuel Macron — and Paul Dupuy received €20m in 2022 and launched their first medical check-up centre in 2023.

Round

Pre-seed

Valuation

Undisclosed


Date

2022

Size

€20m

GlycanAge

Biological age test

Total funding

€4.2m

Newcastle upon Tyne, United Kingdom
2020

This company provides biological age testing kits. Customers send four drops of blood to the lab — after the results come in, they speak to a specialist to see how their lifestyles can be optimised.

Round

Seed

Valuation

Undisclosed


Date

2023

Size

€3.8m

Neko Health

Preventative care

Total funding

€60m

Stockholm, Sweden
2018

Neko Health, a healthtech startup focused on body scanning, co-founded by serial entrepreneur Hjalmar Nilsonne and Spotify founder Daniel Ek, completed a funding round led by Lakestar. Other notable participants included Atomico and General Catalyst.

Round

Series A

Valuation

Undisclosed


Date

2023

Size

€60m

Early stage startups to watch

Actif Age

Lisbon, Portugal
2020
Seed

100k

100k

666k

Advosense

Berlin, Germany
2020
Angel

1.3m

750k

-

Age Labs AS

Oslo, Norway
2017
Bootstrapped

2m

550k

-

Aktiia

Neuchâtel, Switzerland
2018
Series A

24.4m

15.9m

-

Albert Health

Istanbul, Türkiye
2018
Seed

910k

910k

-

Avea Life

Zug, Switzerland
2021
Seed

2.4m

2.1m

-

Aware Health GmbH

Berlin, Germany
2021
Seed

14.1m

10m

-

Biolytica

Zug, Switzerland
2021
Seed

5.3m

5.3m

-

Bioniq health-tech solutions

United Kingdom
2019
Early VC

20.7m

13.6m

-

Care

Winterthur, Switzerland
0
Angel

5m

-

-

Cellbricks

Berlin, Germany
2016
Seed

1.4m

600k

-

Cellvie

Zürich, Switzerland
2018
Early VC

9.6m

5m

-

Cleara Biotech

Utrecht, Netherlands
2018
Seed

2.3m

2.3m

-

Clock Bio

Cambridge, United Kingdom
2020
Early VC

3.6m

3.6m

-

Curexsys

Göttingen, Germany
2020

-

-

-

-

Epiterna

Epalinges, Switzerland
2022
Early VC

10m

10m

-

GlycanAge LTD

Newcastle upon Tyne, United Kingdom
2020
Seed

4.2m

3.8m

18.8m

Healthier

Athens, Greece
2017
Grant

10k

10k

-

Lykon

Berlin, Germany
2015
Early VC

18.9m

2.5m

-

Muhdo

Ipswich, United Kingdom
2016

-

-

-

-

Neko Health

Stockholm, Sweden
2018
Series A

60m

60m

-

Rosita Longevity

Cofrentes, Spain
2020
Seed

2.4m

2.4m

-

Samsara Therapeutics

Oxford, United Kingdom
2018
Grant

-

-

-

Senisca

Exeter, United Kingdom
2020
Grant

2.8m

690k

-

Shift Bioscience

Cambridge, United Kingdom
2017
Seed

6m

5m

-

SmartQare

Eindhoven, Netherlands
2017
Seed

11.8m

1.2m

-

Theblood

Berlin, Germany
2022
Pre-seed

1m

1m

-

Thriva Solutions

London, United Kingdom
2015
Series A

13.7m

4.8m

-

Una Health

Berlin, Germany
2021
Seed

2.6m

2.3m

-

Zoī

Paris, France
2022
Pre-seed

20m

20m

100m

Europe’s success stories

Who early stage startups are up against

(Pre-)Seed

SeriesA

SeriesB

SeriesC

SeriesD+

IPO/Exit

The UK company is working on gene therapies designed to halt or slow the ageing process. In 2022, it became the first European longevity company to go public, listing on the London Stock Exchange. Genflow was founded by Eric Leire, an expert in cell and gene therapy who has led several gene and cell therapy companies, including the Nasdaq-listed Enochian Biosciences.

(Pre-)Seed

SeriesA

SeriesB

SeriesC

SeriesD+

IPO/Exit

A company focused on developing therapies to postpone age-related diseases. In October 2023, Rejuvenate Biomed announced the completion of a six-week study for its lead drug candidate, which has shown promise in elderly male subjects with muscle atrophy.

(Pre-)Seed

SeriesA

SeriesB

SeriesC

SeriesD+

IPO/Exit

Swiss company that sells consumer health products targeting healthy ageing. Timeline raised a $66m Series D round in January 2024, which saw L’Oréal's venture arm Bold take a minority stake in the company.

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