Healthtech in 2023
Some downturn symptoms, but the patient will survive
Last updated: 5 Oct 2023
Market 101
Who’s in rude health this year? If your startup has “AI”, “digital” or “predictive” in its product description, you’re finding investors. Robot makers and startups with wellbeing/longevity pitches are getting attention too.
Many are looking to capitalise on the AI boom to improve patient care, drug discovery and clinical note-taking. One of this year’s biggest healthtech raises to date — a $60m Series B — was for London’s Causaly, which uses AI to speed-read scientific literature, regulatory documents and clinical trials in the hopes of revolutionising the process of discovering new drugs and therapies.
Elsewhere, “techbio” startups are helping companies build computing platforms, as biology moves from bench science to data science. At the cutting edge of medtech, meanwhile, are two clusters of startups on the rise: those trying to hook our brains up to computers, and those making high-precision surgery tools. 2023’s seen breakthroughs for treatments for vexing diseases: medicines for immunologic disorders, and newer modalities such as cell and gene therapies, have renewed interest from investors (though we’re still waiting for a company to make a great leap forward on mRNA — the technology’s success against Covid-19 has yet to be replicated in other vaccines). Weight-loss drugs are the fad of the day and a handful of companies are moving at pace to conquer the European market.
Of course — though it barely needs typing — little of this activity is as bubbly as it was in 2021: the funding decline, which began in earnest last year, signals a return to normalcy now that Covid’s injection to healthcare expenditure has receded. But enthusiasm is still in supply, not least for startups switching focus from disease care to wellness and prevention. Another eye-catching round this year was the €60m Series A for Neko Health, the body-scanning healthtech cofounded by Spotify CEO Daniel Ek, which promises instant results about potential skin conditions, and had people queuing in the Stockholm streets to use it. Longevity ideas have momentum — we’re inundated with media profiles of that 45-year-old American businessman who’s spending millions to look 18 again — and that's being matched by the growth of VC funds to specifically target startups aiming to help people have healthier lives. Healthtech started the year with a bout of illness, like all tech sectors — but the pain has subsided.
Early stage market map
Key facts
$38.1bn
expected revenue for digital health in 20231
60%
fall in total funding in YTD 2023 from 2021’s peak2
124
cancer-related deaths per 100k men in 2023 — 6.5% lower than 20183
Trends to watch
Paging Dr Artificial Intelligence
2023 has been the year of the AI-related healthtech raise. Copenhagen-based Corti bagged one of Denmark’s largest rounds this year: a $60m Series B to build out a GenAI “co-pilot” that follows a patient interaction, and nudges doctors and nurses with suggestions for follow-up questions as well as advice.
French femtech Sonio raised $14m for an AI-powered prenatal screening solution that automates ultrasound reporting, while the UK’s thymia raised £2.7m for its gamified AI approach to diagnosing mental health symptoms and treatment plans.
Biotechs that have announced drugs discovered or developed using AI tools include London-based Exscientia. But some believe the best use of AI in healthcare may turn out to be something more modest for the time being — clinical note-taking and reducing the paper stacks are two promising applications.
Among the big admin-busting deals this year: Brussels-based Awell raised $5m for its digital health platform that automates clinical workflows, while Marseille-based Volta Medical bagged €36m for its AI support tool, which helps physicians identify and annotate heart abnormalities.
Also paging Dr Robot
Robots are scrubbing in for shifts in the operating theatre. The UK’s CMR Surgical netted $165m from big names including SoftBank and Tencent, for a system that promises to shave tens of minutes off procedures, allowing hospitals to pack more surgeries into a day.
Meanwhile, Swiss company Distalmotion bagged $150m this year from US private equity firm Revival Healthcare Capital, as it looks to get FDA approval for its robot “Dexter“ and expand into the US.
And there have been other smaller raises in the sector. France’s Moon Surgical picked up $55.4m in May, compatriot Ganymed Robotics €15m in January and Switzerland’s Nanoflex Robotics $12m in February.
B2C is leaving here with something
European healthtech is overwhelmingly B2B terrain — but direct to consumer wellness and longevity ideas have found investors in 2023.
For example, London-based Jude raised $4.2m to further develop its range of services aimed at promoting better bladder health. In September, Stockholm-based Natural Cycles became the world's first birth control app cleared by US regulator FDA to use Apple Watch data.
Béa Fertility raised £2.5m to launch its at-home fertility treatment in the UK, while Berlin-based eaze netted €1.7m pre-seed for its sleep coaching app.
Longevity treatment clinics are coming: Swiss startup Biolytica, which began life as a tool for clinicians to get a better understanding of patients' health, announced a €5.3m seed round earlier this year — and that it’s expanding its business to serve the wider public.
Skinny love
Weight-loss drugs like Ozempic have taken the US by storm and now startups are racing to win the European market.
August saw two new startups raise money to offer treatment plans using semaglutide — the weight-loss drug sold under brand names like Wegovy and Ozempic — with Danish company Embla landing €10m and Swedish company Yazen netting €3.1m.
Other startups focused on men’s health specifically — including a pair of London-based startups, Manual (backed by Felix Capital and Cherry Ventures) and Numan (backed by Anthemis Group and White Star Capital) — have also offered weight-loss treatments that include semaglutide injections.
Startups tracked by Sifted
Sifted take
2023 dealmaking has seen the continuation of a few slow-burn trends. Robot surgeons are gradually taking on more of healthcare’s insane workload — but so far only top-tier hospitals are ready to absorb the cost of AI software integration for these skillful operators. Elsewhere, the long-held promise of data-driven preventative care gets a boost, with big backer Daniel Ek putting skin in the game. All the while, tracker tech — a thing no one is ever fully sure we need — is still journeying between a consumer proposition with limited appeal to compelling medical device. Then there’s the AI hype machine — which is running so hot there’s barely time to take a considered view on it. Enthusiasm is one thing, but the reality is that healthcare is tightly regulated and has proven uniquely difficult for tech companies to crack in the past.
Rising stars
London-based BioCorteX creates computer simulations to understand drug-bacteria interactions and improve a person's response to treatments. The startup counts VCs Sofinnova Partners and Hoxton Ventures among its investors.
Round
Seed
Valuation
Undisclosed
Date
2023
Size
€4.6m
Backed by Operator Exchange and Possible Ventures, Exakt Health is an app-based physiotherapy startup helping people recover from sports injuries.
Round
Seed
Valuation
Undisclosed
Date
2023
Size
€750K
AI assistant for research departments backed by the European Innovation Council and VC firm Nordic Impact.
Round
Seed
Valuation
Undisclosed
Date
2023
Size
€2.4m
Medtech startup helping people with Parkinson's disease to stay active.
Round
Seed
Valuation
Undisclosed
Date
2023
Size
€1.5m
Early stage startups to watch
AC Bioscience Ltd.
Novel therapeutics
Antibodies and immunotherapies
€6m
€2.5m
€33m
Antiverse
AI drug design
Predicting drug-protein interactions
€4.8m
€2.7m
-
Arctoris
AI drug screening
Prediction of physicochemical property
€10m
€5m
-
AVATAR MEDICAL SAS
Diagnosis & detection
Medical analysis
€2.6m
€1.9m
-
Avea
Prevention
€2.5m
€2.5m
€10m
Awell
Collaboration & communication
€2m
€2m
-
Bella (formerly Baby2Body)
Pregnancy & postnatal
€2.8m
€500k
-
BetterSpace
Care provider
Wellbeing & mindfulness
€3m
€1.5m
-
BioCorteX
AI in drug target discovery
Prediction of new therapeutic use
€4.5m
€4.5m
-
Brightmind.AI
Neurological Disorder Diagnosis and Treatment
€3m
€600k
-
CardiaTec Biosciences
AI in drug target discovery
Indentification and classification of target cells
€1.7m
€1.7m
-
Celeris Therapeutics
AI in chemical synthesis
AI in prediction of reaction yield
€7.3m
€10m
€19.3m
Cradle
AI drug design
AI drug design
€5.5m
€5.5m
-
Cue2Walk International
Neurological therapeutics
€1.9m
€1.5m
€4m
DAME
Menstrual health
€2m
€1m
-
Deepflare
AI drug screening
AI drug screening
€1.5m
€1.5m
-
Epoca
"Sensors, wearables & other hardware"
€2.7m
€1.5m
-
Exakt Health
App-based physiotherapy
€2.5m
€750k
-
Fido
Regulatory Compliance Management Solutions
€6.2m
€5m
€6m
Flow - Meditation for modern life
Care provider
Wellbeing & mindfulness
€1.7m
€500k
-
Frankie Health
Full stack solution
€1.5m
€1.5m
€9m
GlycanAge Ltd
Diagnostics
€1.6m
€416k
-
Grace Health
Predictive analysis & monitoring
Women's health
€5.3m
€2.6m
-
Grace Health
Online chats & consultations
€5.4m
€2.7m
-
hero
Care provider
Wellbeing & mindfulness
€2.6m
€850k
€7.8m
Humanity
Prevention
€4.5m
€2.3m
-
ILoF - Intelligent Lab on Fiber
AI drug design
AI in de novo drug design
€10.3m
€5m
-
Iris.ai
AI in drug target discovery
Prediction of new therapeutic use
€8.4m
€2.4m
-
Juno Bio
Gynecological health
Vaginal microbiome analysis
€1.5m
€1m
-
Jutro medical
Treatment & therapeutics
Telehealth
€7.4m
€6m
-
Kind
Other (specify under 'additional information')
€6.3m
€2.8m
€15m
Komed Health AG
Healthcare operations
Collaboration & communication
€3m
€1.1m
-
Kyan Health
Full stack solution
€1.6m
€1.5m
€7.5m
Lattice Medical
Women's health issues
Breast reconstruction
€5m
€1.3m
-
Libera Bio
Novel therapeutics
Antibodies and immunotherapies
€3.8m
€1.3m
-
Likeminded
Care gateway
Therapy
€3.5m
€3.5m
-
Limbic
Care enabler
Patient management
€1.6m
€587k
-
Limula
Modular solution
€12m
€900k
-
Loop Robots
Robotics
Disinfection
€1.8m
€1.8m
-
machineMD
Assessment & Diagnostics
€6.5m
€3.4m
-
MeeToo Education Ltd
Care provider
Peer support
€1.6m
€848k
-
Mendi Innovations AB
Care enabler
VR & hardware
€5m
€4m
€22m
MicrofluidX
Industrialising cell&gene therapy manufacturing
€5.6m
€4m
-
Mindpax.me
Care enabler
Assessment
€2.5m
€1.3m
€9.2m
mo:re GmbH
Animal free medical research
€400k
€400k
-
Muhdo Health Ltd
Diagnostics
€3.6m
€1.2m
€11m
MYHIXEL
Erectile dysfunction & premature ejaculation
€1.5m
€1m
-
Neroes
Neurological therapeutics
€280k
€280k
€3m
NeuroClues
Neurological Disorder Diagnosis and Treatment
€7.2m
€2.5m
-
Nui Care
Care assistant
€6.3m
€3m
-
Occuity
Vision Healthtech
€7.5m
€3.3m
-
Oliva
Care gateway
Therapy
€7.7m
€5.8m
-
Orbit Health GmbH
Predictive analysis & monitoring
Chronic diseases
€4m
€1m
-
P3Lab
Assessment & Diagnostics
€7.2m
€2.5m
-
PreComb
AI in drug target discovery
Prediction of new therapeutic use
€1.8m
€1.1m
-
Quibim
Health
Medical analysis
€13.6m
€5m
-
QV Bioelectronics
Neurological treatment solutions
€3.6m
€2.6m
-
Sanctus
Care gateway
Coaching
€6.1m
€5.1m
-
SanguisAI
Non-invasive Health Monitoring
€25k
€20k
-
Spill
Care gateway
Therapy
€3m
€2.5m
€13m
SPOKE
Care provider
Wellbeing & mindfulness
€1.6m
€550k
-
Suturion Ab
Remote Patient Monitoring
€400k
€200k
-
thymia
Care enabler
Assessment
€2.4m
€1.4m
€16m
Time is Brain
Neurological Disorder Diagnosis and Treatment
€8.5m
€900k
-
Tomorrow Biostasis
€2.5m
€2.5m
-
Toothfairy™
Diagnosis & detection
Telehealth
€4.2m
€3.5m
-
Tuune
Birth control
€4.2m
€4.1m
-
Vedea Healthware
Vision Healthtech
€1m
€400k
-
Vivan Therapeutics (registered as My Personal Therapeutics LTD.)
Cancer Therapeutics
€5m
€1.8m
-
Your KAYA
Menstrual health
€2.3m
€1.1m
€9.6m
Europe’s success stories
Who early stage startups are up against
(Pre-)Seed
Series A
Series B
Series C
Series D+
IPO/Exit
Cambridge-based company on a mission to revolutionise surgery via advanced modular robots. Cap table includes backers LGT, Tencent, SoftBank and Lightrock among others.
(Pre-)Seed
Series A
Series B
Series C
Series D+
IPO/Exit
The Danish startup is developing a preventative treatment for rare blood clotting disorders. Backers include Maj Invest, HealthCap and Novo Holdings.
(Pre-)Seed
Series A
Series B
Series C
Series D+
IPO/Exit
Swiss startup developing treatments for cancer and fibrotic diseases, which raised a $105m round in April from backers including Bpifrance, Schroders Capital, RA Capital Management and Pureos Bioventures.
(Pre-)Seed
Series A
Series B
Series C
Series D+
IPO/Exit
Develops and manufactures advanced robots for minimally invasive surgeries.
Sources
Data sources
Sifted | Proprietary data
2 Dealroom.co | Data
1 Digital Health - Europe | August 2023 | Statista
Research reports
3 European cancer mortality predictions for the year 2023 with focus on lung cancer | April 2023 | PubMed
The Resilience of Early-stage European Healthtech | July 2023 | Octopus Ventures
Biotech 2.0 | September 2023 | Sifted Pro
Medtech | June 2023 | Sifted Pro
Neurotech | August 2023 | Sifted Pro
News articles
CMR Surgical raises $165m from existing investors SoftBank and Tencent | September 2023 | Sifted
Atomico backs GenAI healthcare assistant Corti’s Series B | September 2023 | Sifted
Ozempic wars — how weight-loss drugs have become a new goldrush in healthtech | September 2023 | Sifted
Peter Thiel invests in UK healthtech speeding up clinical trials | June 2023 | Sifted
Increase your lifespan for €10k with high-powered data from longevity startup Biolytica, which has raised €5.3m | May 2023 | Sifted
Plural's latest investment: $5.3m for tech to free up nurses' time | April 2023 | Sifted
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