Podcast

October 23, 2025

How to build a $100bn company in Europe, with Sequoia's Luciana Lixandru

This week it’s another special episode recorded live at the Sifted Summit, with host Amy sitting down with Sequoia Capital’s Luciana Lixandru.

Luciana, who established the legendary Silicon Valley firm's presence in Europe in 2020, discusses the continent’s Act Two”, and ambitions to build $100bn companies. She talks about what Sequoia looks for in founders, how to build a defensible AI business and why she believes London is becoming the centre of Europe’s AI renaissance.

Luciana and Amy also discuss the resurgence of robotics, why fintech still matters and how founders can balance building in Europe with winning in the US.

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Maya Dharampal-Hornby

Maya Dharampal-Hornby is Sifted's editorial assistant and producer of Startup Europe — The Sifted Podcast .

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